This presentation was originally given as part of Genetic Genealogy Ireland 2019.

Mitochondrial DNA (mtDNA) has the distinct feature of being strictly maternally inherited, making it an indispensable tool for genealogical research of matrilineal ancestors. Within the mtDNA Project for Newfoundland and Labrador one particular mtDNA profile (belonging to haplogroup H5a5) has been found to occur at an unusually high frequency, especially in comparison with how rarely it appears to occur elsewhere. Given the substantial number of Irish who settled in Newfoundland, it is natural to ask whether Ireland is the source of this mtDNA lineage (as well as other mtDNA profiles in Newfoundland). This lecture will highlight what is known of the H5a5 profile in Newfoundland and where it may have originated.