Advanced Topics in DNA 3 of 5: Advanced Relationship Analysis

Blaine Bettinger, Ph.D., J.D.
May 20, 2026
1.7K views
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About this webinar

Learn techniques for advanced relationship analysis using shared cM amounts for two or more DNA test-takers. Includes an introduction to relationship analysis tools such as What are the Odds (WATO) and more. Take relationship analysis to the next level!

About the speaker

Blaine Bettinger, Ph.D., J.D., is a professional genealogist specializing in DNA evidence. In 2007 he started The Genetic Genealogist ( www.thegeneticgenealogist.com ), one of the earliest blogs on th...
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Key points and insights

In the rapidly evolving field of genetic genealogy, moving beyond basic DNA matching is crucial for breaking down brick walls and accurately mapping complex family trees. The "Advanced Relationship Analysis" webinar, featuring renowned DNA expert Blaine Bettinger, provides researchers with sophisticated strategies to unlock the true potential of their genetic data. By shifting the analytical focus from isolated matches to comprehensive datasets, this session demonstrates how advanced methodology can confidently solve intricate relationship puzzles. Whether navigating unexpected match sizes or verifying a specific ancestral line, understanding these advanced techniques is essential for any researcher looking to elevate their genealogical skills and bring clarity to their data.

Key Takeaways

  • Harnessing Meiosis Groupings for Broader Context: Utilizing meiosis groupings—clusters of genealogical relationships that share the identical number of reproductive events—allows researchers to leverage vastly larger datasets. By consulting the comprehensive Shared Centimorgan Project PDF, genealogists can evaluate individual matches against thousands of data submissions rather than isolated tools, providing a much clearer picture of DNA distribution and helping to flag extreme anomalies.
  • Leveraging Results from Siblings and Cousins: A single DNA test represents only one version of genetic inheritance, but incorporating the results of full siblings, shared-side half siblings, or first cousins multiplies analytical power. Researchers can easily harvest these additional data points through direct profile access or enhanced shared matching features on major testing platforms, turning a single match comparison into a robust, multi-person analysis.
  • Reducing Randomness via Averaging and Multi-Amount Tools: Entering multiple centimorgan amounts into multi-box relationship tools can dramatically narrow down potential relationship paths by filtering only for connections that accommodate the widest range of data. Furthermore, averaging the shared DNA amounts of multiple relatives from the same generation helps mitigate the inherent randomness of genetic inheritance, yielding more statistically stable and accurate relationship probabilities.

To fully grasp these advanced techniques and seamlessly apply them to independent research, viewing the complete webinar recording is highly recommended. Watching the presentation provides a deeper look into the practical application of these features, complete with visual walkthroughs and real-world case studies that bring the methodology to life. Additionally, genealogists are encouraged to explore the extensive companion syllabus, which contains valuable resource links, diagrams, and supplementary reference materials designed to guide advanced genetic analysis. Dive into the full session to transform a standard match list into a clear, structured roadmap for ancestral discovery.


Comments (81)

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  1. KH
    Kim Holman
    4 days ago

    Does Ancestry.com understand how much further I could be with my research if they provided the segment data!!!! Annoying!!!

  2. KH
    Kim Holman
    4 days ago

    WOW! That shared DNA adding in siblings is amazing at DNA painter..I have been struggling with if a match is a half first cousin to my grandmother and her siblings I just went and pasted all of their segments with her into this and its 4 of them and it says she would have shared 789 cms with their mother making her this matches half aunt!! Success! I have been pretty sure it was this line of this family this makes it so clear that I was on the right track! Thanks Blaine!!!

  3. CK
    Catherine Kesseler
    8 days ago

    23andme also shows the amount of shared matches share with each other- the amount is given as a percentage and you can't sort you closest to match but it is thre

  4. JT
    Janet Thomson
    8 days ago

    WOW to the nth degree, Blaine! I gained another nugget, thanks to you! I listened to the leveraging section twice today, and I much appreciate your explanations.

  5. PB
    Patricia Briggs
    9 days ago

    Yet another information packed webinar from Blaine Bettinger. Thank you. I will have to watch it again because it is impossible to keep all the Information strait in ones head. Once you use the information and see the outcome it is certainly extremely helpful.

  6. JF
    Justin Friar
    9 days ago

    Very clear, with a good foundational building of the topic and then applying it.

  7. MG
    Marissa Goldenman
    9 days ago

    Most of this was intuitive pattern recognition for me; I don't feel I learned as much this webinar beyond meiosis terminology. I appreciated the tip about the second data set at DNA Painter as it's been awhile since I played there, and the tip about averaging shared matches of the same generation for improving/determining common relationship.

  8. RD
    Rosalyn Dowling
    9 days ago

    Blaine has a way of presenting DNA that's understandable. Very helpful and interesting. Blaine's presentation was understandable, helpful and interesting. Thank you!

Advanced Topics in DNA 3 of 5: Advanced Relationship Analysis - Legacy Family Tree Webinars